Bioinformatics Scientist
Genomines
Paris, France
Posted 6+ months ago
COMPANY DESCRIPTION
At Genomines, our mission is to pioneer a new era of sustainable metal production by farming plants
that hyperaccumulate metal. Through synthetic biology and cutting-edge technology, we harness the power of nature to create plants that can farm for metals while decontaminating soils and creating cleaner lands for agriculture. Our ultimate goal is to become the world's first carbon-negative nickel producer, using sustainable, eco-friendly methods to extract the valuable resources our society needs for the energy transition.
ROLE OVERVIEW
Genomines is seeking a Bioinformatics Scientist will play a key role in advancing genomic research by leading complex analyses across genome, transcriptome, and RNA sequencing datasets. This role requires expertise in assembling and annotating non-bacterial and non-fungal genomes (with a focus on plants and animals), implementing rigorous quality control, and developing computational workflows. The successful candidate will ensure data integrity, reproducibility, and scalability while supporting cross-disciplinary research initiatives. The role will report directly to the CTO & Co-Founder.
RESPONSIBILITIES
- GENOME ASSEMBLY
- Conduct complex genome assemblies, focusing on non-bacterial and non-fungal organisms, with a preference for plant or animal genomes
- Capable of performing comprehensive plant genome assemblies
- Execute relevant quality control measures
- GENOMIC ANNOTATION AND ANALYSIS
- Perform structural and functional annotation of transposable elements
- Critically analyze automated processing workflows
- TRANCSRIPTOME ANALYSIS
- Assemble transcriptomes to explore differences between mutants and original organisms
- RNAseq AND DATA PROCESSING
- Apply RNAseq techniques
- Lead transcriptomic analyses across one or multiple factors, with or without a reference genome
- Establish and conduct quality control procedures
- BIOINFORMATICS PIPELINE AND DEVELOPMENT ENVIRONMENT MANAGEMENT
- Utilize pipeline managers like Snakemake or Nextflow
- Configure and manage isolated development environments, such as coding environments, modules, or Python virtual environments
- DATA AND IT PROCESS MANAGEMENT
- Ensure effective genomic data traceability and associated IT process backups
- Documentation and Reporting: Keep accurate documentation and produce research reports
- Technical Support: Assist in preparing data for analysis and managing databases
QUALIFICATIONS AND EXPERIENCE
- PhD degree in molecular biology, bioinformatics, or a related field
- Fluent in English (both written and spoken); additional language skills are advantageous
- Understand best practices in reproducible science, including tool version control and crafting quality reports, along with developing data management plans
- Experienced in plant genetic engineering techniques such as CRISPR and bacterium-mediated transformation, with a focus on optimization
TECHNICAL AND OPERATIONAL COMPETENCIES
- Demonstrated experience in assembling non-bacterial and non-fungal genomes, preferably plant or animal genomes
- Proficient with IT tools for independent process management, including familiarity with software licensing and usage rights
- Proficient in Linux
- Skilled in Programming Tools and Languages (Competent with GitHub/GitLab for code versioning and Proficient in programming languages like Python and Shell/Bash)
- Knowledgeable in short reads/long reads sequencing technologies
- Familiar with computing and storage systems, including experience with computing clusters and data storage and backup solutions like OVH
SOFT SKILLS
- Collaborative team player with effective communication skills
- Demonstrates scientific rigor and meticulous attention to detail
- Shows adaptability and a commitment to continuous learning
- Possesses humility and openness to growth
POSITION INFORMATION
- Place of Work: Les Ulis, France laboratory, 5 days/week