About Level Zero
Level Zero is pioneering next-generation biosensor technology for precise, real-time monitoring of critical endocrine biomarkers. Recognised as one of the top 20 startups across all categories worldwide at TechCrunch Disrupt 2024—and backed by top-tier organisations like SOSV and Entrepreneur First—we’re pushing the boundaries of biochemistry and nanotechnology to revolutionize personalised health.

Founded by two seasoned engineers, we bring extensive experience in R&D, technical innovation, and commercial strategy to transform the way people monitor their health. Our mission is bold: to revolutionise health management by delivering clinical-grade data directly to individuals, wherever they are.

We’re seeking driven innovators to join us in pushing the boundaries of biosensing and health tech, making personalised health monitoring a reality for everyone. To achieve this ambitious vision, we’re assembling the best team in the world—dedicated to turning cutting-edge science into life-changing, real-world solutions.

About The Role
We are excited to welcome a lead biosensor scientist with a strong background in lateral flow assay R&D, scale-up and experience in working with aptamers to join our rapidly growing start-up. The ideal candidate is expected to be proficient in bench and wet chemistry techniques. Moreover, they should have proven knowledge and experience in assay development and nanoparticle surface modifications (biomolecules, small molecules). It is essential for the candidate to have extensive experience in aptamer-based and antibody-based nanogold colorimetric biosensor R&D, including the designs, operation principles, troubleshooting, and analysis.

This is a full-time, in-person role primarily based in London.
Some examples of what you might do:

Lead the development and the scale-up of LFA components and assay designs.

• Perform conjugation procedures between nanoparticles, aptamers, proteins, and small molecules, as well as the optimisation of such procedures for meeting performance parameters in assays
• Validate aptamer biorecognition and the performance of functional gold nanostructures in different biological medium using colorimetric assays
• Fabricate biosensor devices: working on prototype iteration all the way to mass manufacture
• Analyse and organise raw experimental data as technical reports
• Work closely with the R&D leadership to optimise progress towards R&D milestones
• Attend R&D-related trainings and seminars for continuous updates on the latest trend in hormone sensing technologies
  
  
  
  

What You Bring

• A Ph. D. degree in chemistry, material science, biomedical engineering, bionanotechnology or related discipline, with a focus in aptamer nanobiosensors. At least 4 years of industry experience
  
  
  
  

The ideal candidate will possess expertise in the following areas:

• Proven knowledge and experience in lateral flow assay development with experience launching assays to market
• Proficiency in wet chemistry laboratory techniques, including nanomaterial characterisations and liquid-handling techniques
• Experience and a deep understanding in gold nanostructures: their use in biosensors, synthesis, and the opportunities for surface modifications
• Strong experience in assay development, particularly in unlocking key hurdles (non-specific binding, signal-to-noise enhancement, optimising assay binding conditions)
• Expertise in the R&D of colorimetric nanobiosensors and aptamer biorecognitions
• Understandings of aptamers and small molecules handling skills
• Experience in leading a small team
  
  
  
  

Nice to have:

• Experience in gel electrophoresis and blotting methods
• Experience in metallic nanostructure analytical skill: ICP-MS or ICP-OES
  
  
  
  

Who You Are

• We value culture as much as we value technical expertise, creating an environment that’s equal parts collaboration, curiosity, and fun
  
  
  
  

We’re a fast-paced, mission-driven young team on a quest to make a lasting impact, fueled by uncompromising integrity, unwavering support for one another, and the thrill of exploring uncharted territories. Our passion for excellence drives everything we do, and we welcome individuals who share our commitment to shaping the future.

If our vision excites you, here are the qualities we look for:

• You live and breathe integrity, tackling challenges with honesty and transparency
• You’re a self-starter who loves diving into the unknown, collaborating on complex problems, and taking full ownership of results
• You excel at open, clear communication and see every piece of feedback as a springboard for growth—especially in a science and data-focused environment
• You’re a technical leader capable of balancing complex timelines, motivating your team and streamlining priorities
• You’re motivated by creating real impact, particularly when it comes to advancing human health
• You strike a balance between independence and collaboration, knowing when to seek support or invite others to join in
• You’re confident in defending your ideas, while also valuing respectful, constructive debate as a path to better solutions
• You thrive in the dynamic atmosphere of a startup, constantly evolving your skill set and fearlessly applying what you learn
  
  
  
  

What We Offer

• A full-time role with a competitive salary and equity options, reflecting our value in your expertise and potential
• An environment where you’ll collaborate directly with the founding team at a leading biosensor startup, gaining access to industry experts and thought leaders
• The chance to grow with us, including ample opportunities for leadership, career advancement, and exploration
• Travel to New York and other potential sites for R&D purposes
• The excitement of working on cutting-edge technology, shaping strategic decisions, and driving innovation at an early-stage venture alongside a superstar team
  
  
  
  

Be Part of Our Journey
If you're ready to be at the forefront of biosensing innovation and thrive in fast-paced, learning-rich environments, we'd love to hear from you.

If your skills and experience do not align perfectly with this role, yet you believe you have something unique to offer, we're keen to listen. Reach out to us with a short statement on how you can contribute and let's discuss where you might fit into our team.